Phosphorylation at threonine-654 is not required for negative regulation of the epidermal growth factor receptor by non-phorbol tumor promoters.

Phosphorylation of the epidermal growth factor (EGF) receptor following activation of protein kinase C appears to negatively regulate EGF binding and the receptor-associated tyrosine kinase activity. We have identified two agents, the calcium ionophore A23187 and the non-phorbol tumor promoter thaps...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Friedman, B A, van Amsterdam, J, Fujiki, H, Rosner, M R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC286567/
https://ncbi.nlm.nih.gov/pubmed/2492663
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