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Phosphorylation at threonine-654 is not required for negative regulation of the epidermal growth factor receptor by non-phorbol tumor promoters.

Phosphorylation of the epidermal growth factor (EGF) receptor following activation of protein kinase C appears to negatively regulate EGF binding and the receptor-associated tyrosine kinase activity. We have identified two agents, the calcium ionophore A23187 and the non-phorbol tumor promoter thaps...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Friedman, B A, van Amsterdam, J, Fujiki, H, Rosner, M R
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1989
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286567/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2492663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.3.812
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