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Drosophila Vps4 promotes Epidermal growth factor receptor signaling independently of its role in receptor degradation

Endocytic trafficking of signaling receptors is an important mechanism for limiting signal duration. Components of the Endosomal Sorting Complexes Required for Transport (ESCRT), which target ubiquitylated receptors to intra-lumenal vesicles (ILVs) of multivesicular bodies, are thought to terminate...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Legent, Kevin, Liu, Hui Hua, Treisman, Jessica E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392597/
https://ncbi.nlm.nih.gov/pubmed/25790850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117960
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