A carregar...

COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation

The COP9 signalosome removes Nedd8 modifications from the Cullin subunits of ubiquitin ligase complexes, reducing their activity. Here, we show that mutations in the Drosophila COP9 signalosome subunit 1b (CSN1b) gene increase the activity of ubiquitin ligases that contain Cullin 1. Analysis of CSN1...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Development
Main Authors: Suisse, Annabelle, He, DanQing, Legent, Kevin, Treisman, Jessica E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536928/
https://ncbi.nlm.nih.gov/pubmed/28619822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.148767
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!