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COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation
The COP9 signalosome removes Nedd8 modifications from the Cullin subunits of ubiquitin ligase complexes, reducing their activity. Here, we show that mutations in the Drosophila COP9 signalosome subunit 1b (CSN1b) gene increase the activity of ubiquitin ligases that contain Cullin 1. Analysis of CSN1...
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| Vydáno v: | Development |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Company of Biologists Ltd
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5536928/ https://ncbi.nlm.nih.gov/pubmed/28619822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.148767 |
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