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Dynamic binding orientations direct activity of HIV reverse transcriptase
The reverse transcriptase of human immunodeficiency virus (HIV) catalyzes a series of reactions to convert the single-stranded RNA genome of HIV into double-stranded DNA for host-cell integration. This task requires the multifunctional reverse transcriptase to discriminate a variety of nucleic-acid...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655135/ https://ncbi.nlm.nih.gov/pubmed/18464735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06941 |
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