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Reverse Transcriptase in Motion: Conformational Dynamics of Enzyme-Substrate Interactions

Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) catalyzes synthesis of integration-competent, double-stranded DNA from the single-stranded viral RNA genome, combining both polymerizing and hydrolytic functions to synthesize approximately 20,000 phosphodiester bonds. Despite a we...

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Detaylı Bibliyografya
Asıl Yazarlar: Götte, Matthias, Rausch, Jason W., Marchand, Bruno, Sarafianos, Stefan, Le Grice, Stuart F.J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930377/
https://ncbi.nlm.nih.gov/pubmed/19665597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.07.020
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