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Gα(q) Directly Activates p63RhoGEF and Trio via a Conserved Extension of the Dbl Homology-associated Pleckstrin Homology Domain

The coordinated cross-talk from heterotrimeric G proteins to Rho GTPases is essential during a variety of physiological processes. Emerging data suggest that members of the Gα(12/13) and Gα(q/11) families of heterotrimeric G proteins signal downstream to RhoA via distinct pathways. Although studies...

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Библиографические подробности
Главные авторы: Rojas, Rafael J., Yohe, Marielle E., Gershburg, Svetlana, Kawano, Takeharu, Kozasa, Tohru, Sondek, John
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655113/
https://ncbi.nlm.nih.gov/pubmed/17606614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703458200
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