Blinded Independent Central Review of Progression-Free Survival in Phase III Clinical Trials: Important Design Element or Unnecessary Expense?

Progression-free survival is an important end point in advanced disease settings. Blinded independent central review (BICR) of progression in randomized clinical trials has been advocated to control bias that might result from errors in progression assessments. However, although BICR lessens some po...

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מידע ביבליוגרפי
Main Authors: Dodd, Lori E., Korn, Edward L., Freidlin, Boris, Jaffe, C. Carl, Rubinstein, Lawrence V., Dancey, Janet, Mooney, Margaret M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Clinical Oncology 2008
נושאים:
Statistics in Oncology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654812/
https://ncbi.nlm.nih.gov/pubmed/18669467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.16.1711
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