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Kras regulatory elements and exon 4A determine mutation specificity in lung cancer
KRASis the most frequently mutatedrasfamily member in lung carcinomas1,2, whereasHRASmutations are common in tumours from stratified epithelia such as bladder or skin (www.sanger.ac.uk/genetics/CGP/cosmic/). Using a mouse model (HrasKI)3 in which theHrascoding sequence was inserted into theKraslocus...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654781/ https://ncbi.nlm.nih.gov/pubmed/18758463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.211 |
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