PTCH1 (+/−) Dermal Fibroblasts Isolated from Healthy Skin of Gorlin Syndrome Patients Exhibit Features of Carcinoma Associated Fibroblasts

Gorlin's or nevoid basal cell carcinoma syndrome (NBCCS) causes predisposition to basal cell carcinoma (BCC), the commonest cancer in adult human. Mutations in the tumor suppressor gene PTCH1 are responsible for this autosomal dominant syndrome. In NBCCS patients, as in the general population,...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Valin, Alexandre, Barnay-Verdier, Stéphanie, Robert, Thomas, Ripoche, Hugues, Brellier, Florence, Chevallier-Lagente, Odile, Avril, Marie-Françoise, Magnaldo, Thierry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654107/
https://ncbi.nlm.nih.gov/pubmed/19287498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004818
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi