PTCH1 (+/−) Dermal Fibroblasts Isolated from Healthy Skin of Gorlin Syndrome Patients Exhibit Features of Carcinoma Associated Fibroblasts

Gorlin's or nevoid basal cell carcinoma syndrome (NBCCS) causes predisposition to basal cell carcinoma (BCC), the commonest cancer in adult human. Mutations in the tumor suppressor gene PTCH1 are responsible for this autosomal dominant syndrome. In NBCCS patients, as in the general population,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Valin, Alexandre, Barnay-Verdier, Stéphanie, Robert, Thomas, Ripoche, Hugues, Brellier, Florence, Chevallier-Lagente, Odile, Avril, Marie-Françoise, Magnaldo, Thierry
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2009
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654107/
https://ncbi.nlm.nih.gov/pubmed/19287498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004818
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