HIV gp120 Induces, NF-κB Dependent, HIV Replication that Requires Procaspase 8

BACKGROUND: HIV envelope glycoprotein gp120 causes cellular activation resulting in anergy, apoptosis, proinflammatory cytokine production, and through an unknown mechanism, enhanced HIV replication. METHODOLOGY/PRINCIPAL FINDINGS: We describe that the signals which promote apoptosis are also respon...

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Autors principals: Bren, Gary D., Trushin, Sergey A., Whitman, Joe, Shepard, Brett, Badley, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653723/
https://ncbi.nlm.nih.gov/pubmed/19287489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004875
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