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SDF-1α degrades, while gp120 upregulates Bim(EL): implications for the development of T cell memory

Following a primary immune response, T cell memory occurs when a subset of antigen specific T cells resist peripheral selection by acquiring resistance to TCR induced death. Recent data have implicated Bim as an essential mediator of the contraction phase of T cell immunity. Herein, we describe that...

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Autori principali: Trushin, Sergey A., Carena, Alberto A., Bren, Gary D., Rizza, Stacey A., Dong, Xiangyang, Abraham, Roshini S., Badley, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530261/
https://ncbi.nlm.nih.gov/pubmed/22802411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100275
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