Regulation of shear-induced nuclear translocation of the Nrf2 transcription factor in endothelial cells

BACKGROUND: Vascular endothelial cells (ECs) constantly experience fluid shear stresses generated by blood flow. Laminar flow is known to produce atheroprotective effects on ECs. Nrf2 is a transcription factor that is essential for the antioxidant response element (ARE)-mediated induction of genes s...

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Bibliografiska uppgifter
Huvudupphovsmän: Hsieh, Chung-Yu, Hsiao, Huai-Yu, Wu, Wan-Yi, Liu, Ching-Ann, Tsai, Yu-Chih, Chao, Yuen-Jen, Wang, Danny L, Hsieh, Hsyue-Jen
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2009
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653516/
https://ncbi.nlm.nih.gov/pubmed/19272177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-16-12
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