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Reversal of multi-drug resistance by pSUPER-shRNA-mdr1 in vivo and in vitro
AIM: To explore the possibility of reversing multi-drug resistance (MDR) to HepG2/mdr1 in vitro and in vivo with RNA interference (RNAi). METHODS: HepG2/mdr1 was obtained by cloning the whole gene mdr1 into HepG2 cells. shRNA targeting sequence was designed to be homologous to the P-gp encoding MDR1...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The WJG Press and Baishideng
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653364/ https://ncbi.nlm.nih.gov/pubmed/19152447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.15.431 |
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