A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries

BACKGROUND: The identification of novel drug targets by assessing gene functions is most conveniently achieved by high-throughput loss-of-function RNA interference screening. There is a growing need to employ primary cells in such screenings, since they reflect the physiological situation more close...

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Détails bibliographiques
Auteurs principaux: Oehmig, Angelika, Klotzbücher, Andrea, Thomas, Maria, Weise, Frank, Hagner, Ursula, Brundiers, Ralf, Waldherr, Dirk, Lingnau, Andreas, Knappik, Achim, Kubbutat, Michael HG, Joos, Thomas O, Volkmer, Hansjürgen
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Methodology Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2559852/
https://ncbi.nlm.nih.gov/pubmed/18816379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-441
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