Reversal of multidrug resistance by magnetic Fe(3)O(4) nanoparticle copolymerizating daunorubicin and MDR1 shRNA expression vector in leukemia cells

In many instances, multidrug resistance (MDR) is mediated by increasing the expression at the cell surface of the MDR1 gene product, P-glycoprotein (P-gp), a 170-kD energy-dependent efflux pump. The aim of this study was to investigate the potential benefit of combination therapy with magnetic Fe(3)...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Chen, Bao-an, Mao, Pei-pei, Cheng, Jian, Gao, Feng, Xia, Guo-hua, Xu, Wen-lin, Shen, Hui-lin, Ding, Jia-hua, Gao, Chong, Sun, Qian, Chen, Wen-ji, Chen, Ning-na, Liu, Li-jie, Li, Xiao-mao, Wang, Xue-mei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2010
Onderwerpen:
Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950401/
https://ncbi.nlm.nih.gov/pubmed/20957165
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items