Daunorubicin-loaded magnetic nanoparticles of Fe(3)O(4) overcome multidrug resistance and induce apoptosis of K562-n/VCR cells in vivo

Multidrug resistance (MDR) is a major obstacle to cancer chemotherapy. We evaluated the effect of daunorubicin (DNR)-loaded magnetic nanoparticles of Fe(3)O(4) (MNPs-Fe(3)O(4)) on K562-n/VCR cells in vivo. K562-n and its MDR counterpart K562-n/VCR cell were inoculated into nude mice subcutaneously....

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Detalhes bibliográficos
Main Authors: Chen, Bao-an, Lai, Bin-bin, Cheng, Jian, Xia, Guo-hua, Gao, Feng, Xu, Wen-lin, Ding, Jia-hua, Gao, Chong, Sun, Xin-chen, Xu, Cui-rong, Chen, Wen-ji, Chen, Ning-na, Liu, Li-jie, Li, Xiao-mao, Wang, Xue-mei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775690/
https://ncbi.nlm.nih.gov/pubmed/19918366
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