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Bacterial artificial chromosomes improve recombinant protein production in mammalian cells

BACKGROUND: The development of appropriate expression vectors for large scale protein production constitutes a critical step in recombinant protein production. The use of conventional expression vectors to obtain cell lines is a cumbersome procedure. Often, stable cell lines produce low protein yiel...

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Hlavní autoři: Blaas, Leander, Musteanu, Monica, Eferl, Robert, Bauer, Anton, Casanova, Emilio
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653024/
https://ncbi.nlm.nih.gov/pubmed/19144171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-3
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