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Generation of recombinant MVA-norovirus: a comparison study of bacterial artificial chromosome- and marker-based systems

BACKGROUND: Recombinant Modified Vaccinia Virus Ankara has been employed as a safe and potent viral vector vaccine against infectious diseases and cancer. We generated recMVAs encoding norovirus GII.4 genotype capsid protein by using a marker-based approach and a BAC-based system. In the marker-base...

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Publicat a:Virol J
Autors principals: Kugler, Franziska, Drexler, Ingo, Protzer, Ulrike, Hoffmann, Dieter, Moeini, Hassan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688233/
https://ncbi.nlm.nih.gov/pubmed/31399106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-019-1212-y
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