Point mutation of bacterial artificial chromosomes by ET recombination

Bacterial artificial chromosomes (BACs) offer many advantages for functional studies of large eukaryotic genes. To utilize the potential applications of BACs optimally, new approaches that allow rapid and precise engineering of these large molecules are required. Here, we describe a simple and flexi...

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Autores principales: Muyrers, Joep P.P., Zhang, Youming, Benes, Vladimir, Testa, Giuseppe, Ansorge, Wilhelm, Stewart, A. Francis
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2000
Materias:
Scientific Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083723/
https://ncbi.nlm.nih.gov/pubmed/11256606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd049
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