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LITHOCHOLIC ACID DECREASES EXPRESSION OF UGT2B7 IN CACO-2 CELLS: A POTENTIAL ROLE FOR A NEGATIVE FARNESOID X RECEPTOR RESPONSE ELEMENT

Human UDP-glucuronosyltransferase (UGT) 2B7 is the major isoform catalyzing the glucuronidation of a variety of endogenous compounds including bile acids. To determine the role of bile acids in the regulation of UGT2B7 expression, Caco-2 cells were incubated with the natural human farnesoid X recept...

詳細記述

保存先:
書誌詳細
主要な著者: Lu, Yuan, Heydel, Jean-Marie, Li, Xin, Bratton, Stacie, Lindblom, Tim, Radominska-Pandya, Anna
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652669/
https://ncbi.nlm.nih.gov/pubmed/15821044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.104.003061
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