Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs

A diet high in fat induces cardiac hypertrophy, inflammation, and oxidative stress. Although such actions have largely been ascribed to fat deposition, the accumulation of advanced glycation end products (AGEs) and subsequent activation of the receptor for AGEs (RAGE) may also represent important me...

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Autori principali: Tikellis, Christos, Thomas, Merlin C., Harcourt, Brooke E., Coughlan, Melinda T., Pete, Josepha, Bialkowski, Katarzyna, Tan, Adeline, Bierhaus, Angelika, Cooper, Mark E., Forbes, Josephine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652498/
https://ncbi.nlm.nih.gov/pubmed/18477705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00024.2008
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