Dysfunctional homologous recombination mediates genomic instability and progression in myeloma

A prominent feature of most if not all cancers is a striking genetic instability, leading to ongoing accrual of mutational changes, some of which underlie tumor progression, including acquisition of invasiveness, drug resistance, and metastasis. Thus, the molecular basis for the generation of this g...

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Bibliographic Details
Main Authors: Shammas, Masood A., Shmookler Reis, Robert J., Koley, Hemanta, Batchu, Ramesh B., Li, Cheng, Munshi, Nikhil C.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2009
Subjects:
Lymphoid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652372/
https://ncbi.nlm.nih.gov/pubmed/19050310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-089193
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