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Dysfunctional homologous recombination mediates genomic instability and progression in myeloma

A prominent feature of most if not all cancers is a striking genetic instability, leading to ongoing accrual of mutational changes, some of which underlie tumor progression, including acquisition of invasiveness, drug resistance, and metastasis. Thus, the molecular basis for the generation of this g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shammas, Masood A., Shmookler Reis, Robert J., Koley, Hemanta, Batchu, Ramesh B., Li, Cheng, Munshi, Nikhil C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652372/
https://ncbi.nlm.nih.gov/pubmed/19050310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-089193
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