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KSR1 Is Required for Cell Cycle Reinitiation Following DNA Damage
KSR1 (kinase suppressor of Ras 1) is a molecular scaffold and positive regulator of the Raf/MEK/ERK phosphorylation cascade. KSR1 is required for maximal ERK activation induced by growth factors and by some cytotoxic agents. We show here that KSR1 is also required for maximal ERK activation induced...
Shranjeno v:
| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2652329/ https://ncbi.nlm.nih.gov/pubmed/19147494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806457200 |
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