Severe Plasmodium falciparum Malaria Is Associated with Circulating Ultra-Large von Willebrand Multimers and ADAMTS13 Inhibition

Plasmodium falciparum infection results in adhesion of infected erythrocytes to blood vessel endothelium, and acute endothelial cell activation, together with sequestration of platelets and leucocytes. We have previously shown that patients with severe infection or fulminant cerebral malaria have si...

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Détails bibliographiques
Auteurs principaux: Larkin, Deirdre, de Laat, Bas, Jenkins, P. Vince, Bunn, James, Craig, Alister G., Terraube, Virginie, Preston, Roger J. S., Donkor, Cynthia, Grau, George E., van Mourik, Jan A., O'Donnell, James S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652105/
https://ncbi.nlm.nih.gov/pubmed/19300493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000349
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