Rapid activation of endothelial cells enables P. falciparum adhesion to platelet decorated von Willebrand factor strings

During Plasmodium falciparum malaria infections, von Willebrand factor (VWF) levels are elevated, post-mortem studies show platelets co-localised with sequestered infected erythrocytes (IE) at brain microvascular sites, while in vitro studies have demonstrated platelet-mediated IE adhesion to TNF-ac...

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Detalhes bibliográficos
Main Authors: Bridges, Daniel J., Bunn, James, van Mourik, Jan A., Grau, Georges, Preston, Roger J.S., Molyneux, Malcolm, Combes, Valery, O'Donnell, James S., de Laat, Bas, Craig, Alister
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840836/
https://ncbi.nlm.nih.gov/pubmed/19897581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235150
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