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β-Selection: Abundance of TCRβ(–)/γδ(–) CD44(–)CD25(–) (DN4) cells in the foetal thymus
Expression of TCRβ and pre-TCR signalling are essential for differentiation of CD4(–)CD8(–) double negative (DN) thymocytes to the CD4(+)CD8(+) double-positive (DP) stage. Thymocyte development in adult Rag1, Rag2 or TCRβδ-deficient mice is arrested at the DN3 stage leading to the assumption that pr...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
WILEY-VCH Verlag
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651467/ https://ncbi.nlm.nih.gov/pubmed/17273993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200636503 |
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