Lipotoxic heart disease in obese rats: Implications for human obesity

To determine the mechanism of the cardiac dilatation and reduced contractility of obese Zucker Diabetic Fatty rats, myocardial triacylglycerol (TG) was assayed chemically and morphologically. TG was high because of underexpression of fatty acid oxidative enzymes and their transcription factor, perox...

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Bibliografische gegevens
Hoofdauteurs: Zhou, Yan-Ting, Grayburn, Paul, Karim, Asad, Shimabukuro, Michio, Higa, Moritake, Baetens, Dany, Orci, Lelio, Unger, Roger H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26513/
https://ncbi.nlm.nih.gov/pubmed/10677535
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