Lipotoxic heart disease in obese rats: Implications for human obesity

To determine the mechanism of the cardiac dilatation and reduced contractility of obese Zucker Diabetic Fatty rats, myocardial triacylglycerol (TG) was assayed chemically and morphologically. TG was high because of underexpression of fatty acid oxidative enzymes and their transcription factor, perox...

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Autors principals: Zhou, Yan-Ting, Grayburn, Paul, Karim, Asad, Shimabukuro, Michio, Higa, Moritake, Baetens, Dany, Orci, Lelio, Unger, Roger H.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC26513/
https://ncbi.nlm.nih.gov/pubmed/10677535
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