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Lipotoxic heart disease in obese rats: Implications for human obesity

To determine the mechanism of the cardiac dilatation and reduced contractility of obese Zucker Diabetic Fatty rats, myocardial triacylglycerol (TG) was assayed chemically and morphologically. TG was high because of underexpression of fatty acid oxidative enzymes and their transcription factor, perox...

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主要な著者: Zhou, Yan-Ting, Grayburn, Paul, Karim, Asad, Shimabukuro, Michio, Higa, Moritake, Baetens, Dany, Orci, Lelio, Unger, Roger H.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2000
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC26513/
https://ncbi.nlm.nih.gov/pubmed/10677535
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