Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model

Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion death. We hypothesize that TRALI requires 2 events: (1) the clinical condition of the patient and (2) the infusion of antibodies against MHC class I antigens or the plasma from stored blood. A 2-event rat model was dev...

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Hauptverfasser: Kelher, Marguerite R., Masuno, Tomhiko, Moore, Ernest E., Damle, Sagar, Meng, Xianzhong, Song, Yong, Liang, Xiayuan, Niedzinski, Jerry, Geier, Steven S., Khan, Samina Y., Gamboni-Robertson, Fabia, Silliman, Christopher C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Transfusion Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651018/
https://ncbi.nlm.nih.gov/pubmed/19131548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-177857
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