Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury

Transfusion-related acute lung injury (TRALI) is a form of posttransfusion acute pulmonary insufficiency that has been linked to the infusion of biologic response modifiers (BRMs), including antileukocyte antibodies and lipids. Soluble CD40 ligand (sCD40L) is a platelet-derived proinflammatory media...

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Main Authors: Khan, Samina Yasmin, Kelher, Marguerite R., Heal, Joanna M., Blumberg, Neil, Boshkov, Lynn K., Phipps, Richard, Gettings, Kelly F., McLaughlin, Nathan J., Silliman, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Hematology 2006
Assuntos:
Transfusion Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895564/
https://ncbi.nlm.nih.gov/pubmed/16772606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-017251
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