Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis

Enhanced angiogenesis is a hallmark of cancer. Pleiotrophin (PTN) is an angiogenic factor that is produced by many different human cancers and stimulates tumor blood vessel formation when it is expressed in malignant cancer cells. Recent studies show that monocytes may give rise to vascular endothel...

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Detalhes bibliográficos
Main Authors: Chen, Haiming, Campbell, Richard A., Chang, Yunchao, Li, Mingjie, Wang, Cathy S., Li, Jennifer, Sanchez, Eric, Share, Michael, Steinberg, Jeffrey, Berenson, Ariana, Shalitin, Dror, Zeng, Zhaohui, Gui, Dorina, Perez-Pinera, Pablo, Berenson, Ronald J., Said, Jonathan, Bonavida, Benjamin, Deuel, Thomas F., Berenson, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651013/
https://ncbi.nlm.nih.gov/pubmed/19060246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-133751
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