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Dominant Negative Pleiotrophin Induces Tetraploidy and Aneuploidy in U87MG Human Glioblastoma Cells

Pleiotrophin (PTN, Ptn) is an 18 kD secretory cytokine that is expressed in many human cancers, including glioblastoma. In previous experiments, interruption of the constitutive PTN signaling in human U87MG glioblastoma cells that inappropriately express endogenous Ptn reversed their rapid growth in...

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Detalhes bibliográficos
Main Authors: Chang, Yunchao, Berenson, James R., Wang, Zhaoyi, Deuel, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850963/
https://ncbi.nlm.nih.gov/pubmed/17067552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.09.148
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