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Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis

Insulin-induced gene 2 (Insig2) was recently identified as a putative positive prognostic biomarker for colon cancer prognosis. Insig2 has been previously reported to be an endoplasmic reticulum (ER) membrane protein, and a negative regulator of cholesterol synthesis. Here we report that Insig2 was...

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Autori principali: Li, Chang Gong, Gruidl, Mike, Eschrich, Steven, McCarthy, Susan, Wang, Hong-Gang, Alexandrow, Mark G., Yeatman, Timothy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650850/
https://ncbi.nlm.nih.gov/pubmed/18464289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23510
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