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Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis
Insulin-induced gene 2 (Insig2) was recently identified as a putative positive prognostic biomarker for colon cancer prognosis. Insig2 has been previously reported to be an endoplasmic reticulum (ER) membrane protein, and a negative regulator of cholesterol synthesis. Here we report that Insig2 was...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650850/ https://ncbi.nlm.nih.gov/pubmed/18464289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23510 |
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