INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis

The INO80 chromatin-remodeling complex performs functions in many chromosomal processes that are crucial for genome stability, such as DNA replication and stalled replication fork recovery. Although these functions suggest that INO80 acts as a tumor suppressor, its specific role in tumorigenesis has...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Lee, Shin-Ai, Lee, Han-Sae, Hur, Shin-Kyoung, Kang, Sang Won, Oh, Goo Taeg, Lee, Daekee, Kwon, Jongbum
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777752/
https://ncbi.nlm.nih.gov/pubmed/29383140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22984
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