INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis

The INO80 chromatin-remodeling complex performs functions in many chromosomal processes that are crucial for genome stability, such as DNA replication and stalled replication fork recovery. Although these functions suggest that INO80 acts as a tumor suppressor, its specific role in tumorigenesis has...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Lee, Shin-Ai, Lee, Han-Sae, Hur, Shin-Kyoung, Kang, Sang Won, Oh, Goo Taeg, Lee, Daekee, Kwon, Jongbum
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777752/
https://ncbi.nlm.nih.gov/pubmed/29383140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22984
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