Identification, Characterization, and Azole-Binding Properties of Mycobacterium smegmatis CYP164A2, a Homolog of ML2088, the Sole Cytochrome P450 Gene of Mycobacterium leprae

The genome sequence of Mycobacterium leprae revealed a single open reading frame, ML2088 (CYP164A1), encoding a putative full-length cytochrome P450 monooxygenase and 12 pseudogenes. We have identified a homolog of ML2088 in Mycobacterium smegmatis and report here the cloning, expression, purificati...

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Main Authors: Warrilow, Andrew G. S., Jackson, Colin J., Parker, Josie E., Marczylo, Timothy H., Kelly, Diane E., Lamb, David C., Kelly, Steven L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2009
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Mechanisms of Action: Physiological Effects
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650583/
https://ncbi.nlm.nih.gov/pubmed/19075057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01237-08
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