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Tyrosine sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry
The HIV-1 coreceptor CCR5 possesses tyrosine sulfate (TYS) residues at its N-terminus (Nt) that are required for binding HIV-1 gp120 and mediating viral entry. Using a 14-residue fragment of CCR5 Nt containing two TYS residues, we recently showed that CCR5 Nt binds gp120 through a conserved region s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650494/ https://ncbi.nlm.nih.gov/pubmed/18952441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.10.005 |
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