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Expression, purification and crystallization of the cofactor-independent monooxygenase SnoaB from the nogalamycin biosynthetic pathway

12-deoxy-nogalonic acid oxygenase (SnoaB) catalyzes the oxygenation of 12-deoxy-nogalonic acid at position 12 to yield nogalonic acid, which is one of the steps in the biosynthesis of the polyketide nogalamycin in Streptomyces nogalater. SnoaB belongs to a family of small cofactor-free oxygenases wh...

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Bibliographic Details
Main Authors: Koskiniemi, Hanna, Grocholski, Thadee, Schneider, Gunter, Niemi, Jarmo
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650448/
https://ncbi.nlm.nih.gov/pubmed/19255477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109001389
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