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Polycystin 1 is required for the structural integrity of blood vessels

Autosomal dominant polycystic kidney disease (ADPKD), often caused by mutations in the PKD1 gene, is associated with life-threatening vascular abnormalities that are commonly attributed to the frequent occurrence of hypertension. A previously reported targeted mutation of the mouse homologue of PKD1...

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Bibliografische gegevens
Hoofdauteurs: Kim, Keetae, Drummond, Iain, Ibraghimov-Beskrovnaya, Oxana, Klinger, Katherine, Arnaout, M. Amin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26504/
https://ncbi.nlm.nih.gov/pubmed/10677526
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