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Effect of Oral Treatment with (S)-HPMPA, HDP-(S)-HPMPA or ODE-(S)-HPMPA on Replication of Murine Cytomegalovirus (MCMV) or Human Cytomegalovirus (HCMV) in Animal Models

We utilized BALB/c mice infected with murine CMV (MCMV) or severe combined immunodeficient (SCID) mice implanted with human fetal tissue and infected with HCMV to determine the efficacy of (S)-9-[3-hydroxy-2-(phophonomethoxy)propyl]adenine ((S)-HPMPA), hexadecyloxypropyl-(S)-HPMPA (HDP-(S)-HPMPA), o...

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Bibliografiske detaljer
Main Authors: Quenelle, Debra C., Collins, Deborah J., Pettway, Latisha R., Hartline, Caroll B., Beadle, James R., Wan, W. Brad, Hostetler, Karl Y., Kern, Earl R.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650230/
https://ncbi.nlm.nih.gov/pubmed/18336926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2008.01.155
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