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Mouse models of Huntington disease: variations on a theme

An accepted prerequisite for clinical trials of a compound in humans is the successful alleviation of the disease in animal models. For some diseases, however, successful translation of drug effects from mouse models to the bedside has been limited. One question is whether the current models accurat...

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Bibliografiske detaljer
Main Authors: Ehrnhoefer, Dagmar E., Butland, Stefanie L., Pouladi, Mahmoud A., Hayden, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Limited 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650190/
https://ncbi.nlm.nih.gov/pubmed/19259385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.002451
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