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Small changes, big impact: Posttranslational modifications and function of huntingtin in Huntington disease
Huntington disease (HD) is a neurodegenerative disorder caused by an elongated polyglutamine tract in huntingtin (htt). Htt normally undergoes different posttranslational modifications (PTMs), including phosphorylation, SUMOylation, ubiquitination, acetylation, proteolytic cleavage and palmitoylatio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3200085/ https://ncbi.nlm.nih.gov/pubmed/21311053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1073858410390378 |
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