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Efficient gene therapy-based method for the delivery of therapeutics to primate cortex
Transduction of the primate cortex with adeno-associated virus (AAV)-based gene therapy vectors has been challenging, because of the large size of the cortex. We report that a single infusion of AAV2 vector into thalamus results in widespread expression of transgene in the cortex through transductio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650169/ https://ncbi.nlm.nih.gov/pubmed/19193857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810682106 |
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