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Reduced Macrophage Apoptosis Is Associated With Accelerated Atherosclerosis in Low-Density Lipoprotein Receptor-Null Mice

OBJECTIVE: The majority of apoptotic cells in atherosclerotic lesions are macrophages. However, the pathogenic role of macrophage apoptosis in the development of atherosclerosis remains unclear. Elevated expression of Bax, one of the pivotal proapoptotic proteins of the Bcl-2 family, has been found...

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מידע ביבליוגרפי
Main Authors: Liu, June, Thewke, Douglas P., Su, Yan Ru, Linton, MacRae F., Fazio, Sergio, Sinensky, Michael S.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649706/
https://ncbi.nlm.nih.gov/pubmed/15499039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.ATV.0000148548.47755.22
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