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Reduced Macrophage Apoptosis Is Associated With Accelerated Atherosclerosis in Low-Density Lipoprotein Receptor-Null Mice

OBJECTIVE: The majority of apoptotic cells in atherosclerotic lesions are macrophages. However, the pathogenic role of macrophage apoptosis in the development of atherosclerosis remains unclear. Elevated expression of Bax, one of the pivotal proapoptotic proteins of the Bcl-2 family, has been found...

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Sonraí Bibleagrafaíochta
Main Authors: Liu, June, Thewke, Douglas P., Su, Yan Ru, Linton, MacRae F., Fazio, Sergio, Sinensky, Michael S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2004
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649706/
https://ncbi.nlm.nih.gov/pubmed/15499039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.ATV.0000148548.47755.22
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