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Acyl-coenzyme A: cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages
7-Ketocholesterol (7KC) is a cytotoxic component of oxidized low density lipoproteins (OxLDLs) and induces apoptosis in macrophages by a mechanism involving the activation of cytosolic phospholipase A(2) (cPLA(2)). In the current study, we examined the role of ACAT in 7KC-induced and OxLDL-induced a...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768430/ https://ncbi.nlm.nih.gov/pubmed/15995174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M500101-JLR200 |
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